February 17, 2005

For Immediate Release

Tissue-Based Heart Valves and Annuloplasty Rings Demonstrating Double Digit Growth, According to February Issue of MedMarkets

FOOTHILL RANCH, CAŚ Global sales of mechanical and tissue heart valves stand at nearly $900 million annually, and while the mechanical valve segment is growing at a stable 4%, the tissue segment, including porcine and bovine valves, represents over a third of this market and is growing at 14% annually.

Leaders in the valve market include Edwards Life Sciences, St. Jude Medical, Sorin, Medtronic and others (3F, ATS, CryoLife, and Medical CV and others).

The bulk of valve surgeries are for aortic replacement/repair, followed by mitral valves.

On the horizon, developments in replacement of valves percutaneously offer the potential to not only treat segments of the population contraindicated for open surgery, but also to offer a minimally invasive alternative for all valve surgeries, leading to a global market of in excess of $1 billion.  Last year, Edwards Life Sciences acquired privately held Percutaneous Valve Technologies for $125 million to pursue this huge opportunity.

The article on heart valve technologies in the February 2005 issue of MedMarkets reviews mechanical valves, tissue valves, and the market size, competitors shares and clinical, technology and market trends shaping this evolving market.  Topics covered in the February MedMarkets are outlined here.

MedMarket Diligence provides tactical decision-making solutions on medical technology to the medical products and investment industries. The company publishes the MedMarkets newsletter, a monthly analysis of the market implications of new medical technology and dedicated reports on technology markets.  For additional details, contact Patrick Driscoll at email or call 949-859-3401 or toll-free (in the U.S.). 1-866-820-1357.