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The report described below has been updated by the new Ablation Technologies Report,
Published September 2008

 Ablation Technologies Worldwide Market, 2008-2017: 
Products, Technologies, Markets, Companies and Opportunities

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Products, Technologies, Markets, Companies and Opportunities

Market Opportunities in Ablation Technology

April 2002

Report #S101

This report covers selected technologies and market applications in therapeutic tissue ablation. Specific high growth opportunities include cardiac, tumor ablation, BPH and endometrial ablation. The report details the status of products and technologies currently on the market and under development in each, the competitors and their current and forecast market positions. The report reviews applications, clinical trends, market/technology trends, and the opportunities for current and hopeful competitors in this market.

Table of Contents

Executive Summary

Benign Prostatic Hyperplasia

Endometrial Ablation

Targeted Tumor Ablation

Cardiac Arrhythmia Management

Section 1: Introduction

1.1 Overview of Ablative Surgery

1.2 Current Technologies Used For Ablative Surgery

1.2.1 Monopolar electrocautery

1.2.2 Bipolar electrocautery

1.2.3 Laser

1.2.4 Radiofrequency

1.2.5 Cryoablation

1.2.6 Microwave

1.2.7 High Intensity Focused Ultrasound

1.2.8 Argon beam coagulator

1.2.9 Microwave Technology

1.2.9.1 Surgical Applications of Microwave Ablation Technology

1.2.9.2 Transcatheter Technique

1.2.10 Radiofrequency Technology

1.2.10.1 Surgical Applications of RF Technology

1.2.10.2 Focused Tissue Ablation

1.2.10.3 Conducting Media-Assisted Linear Ablation

1.2.10.4 Tissue Denaturation

1.2.11 Cryogenics Technology

1.2.11.1 Surgical applications of cryogenics

1.2.11.2 Routine Cryosurgery

1.2.11.3 Transcatheter Cryosurgery

1.2.12 Focused Ultrasound Technology

1.2.12.1 Types Of Surgical Focused Ultrasound Systems

1.2.12.2 Directed Shock Wave Devices

1.2.12.3 Focal Ablation Devices

1.2.12.4 Established and Potential Uses of Focused Ultrasound Systems

1.2.12.5 Phased Array Devices

Section 2:  Major Clinical Applications of Ablative Surgical Systems

2.1 OB/GYN Surgery

2.1.1 Endometrial Ablation

2.1.1.1 Symptoms and Diagnosis

2.1.1.2 Treatment

2.1.1.3 Prevalence and Incidence

2.1.1.4 CryoGen Corp.

2.1.1.5 BEI Medical

2.1.1.6 Novacept

2.1.1.7 Gynecare

2.1.1.8 Microsulis

2.1.1.9 Karl Storz/ESC

2.1.1.10 Impres Medical

2.1.1.11 Unique Upside Potential

2.1.1.12 Factors for Success

2.2 Urology

2.2.1 Kidney Stone Removal (Lithotripsy)

2.2.2 Prevalence and Incidence

2.2.3 Benign Prostatic Hyperplasia

2.2.3.1 TUMT

2.2.3.2 Transurethral Needle Ablation (TUNA)

2.2.3.3 Interstitial Laser Coagulation (ILC)

2.2.3.4 Water-Induced Therapy (WIT)

2.2.3.5 On the Horizon

2.2.4 Patient Caseloads, Procedure Volumes, & End Use Trends

2.3 Cardiac Surgery

2.3.1 Arrhythmia Correction

2.3.1.1 Arrhythmia Ablation

2.3.1.2 Atrial Fibrillation

2.3.1.3 Ventricular Tachycardia

2.3.1.3.1 Cryoablation Techniques for Tachyarrhythmia Management

2.3.1.3.2 Arrhythmia Ablation Procedure Volumes

2.3.2 Ischemic reversal

2.3.3 Patient Caseloads, Procedure Volumes, and End Use Trends

2.4 Oncologic Surgery

2.4.1 Primary Liver Cancer

2.4.1.1 Incidence

2.4.1.1.1 Possible causes of primary liver cancer

2.4.1.1.2 Symptoms

2.4.1.1.3 Disease progression/prognosis

2.4.1.2 Metastatic liver tumors

2.4.1.3 Determining treatment options

2.4.2 Colorectal Cancer

2.4.2.1 Incidence

2.4.2.2 Prognosis

2.4.3 Neuroendocrine liver metastases

2.4.4 Targeted Tumor Ablation

2.4.4.1 Companies

2.4.4.1.1 RITA Medical

2.4.4.1.2 Radio Therapeutics Corporation

2.4.5 Photo Dynamic Therapy

2.4.5.1 Principles of Photodynamic Therapy

2.4.5.2 PDT Products and Technologies Under Development

2.4.5.3 Photodynamic Therapy Products

2.4.5.4 PDT Market Forecast

Section 3: U.S. Markets for Ablative Surgical Systems

3.1 Microwave Ablation Systems

3.1.1 Industry Product Offering

3.1.2 Market Forecast

3.1.3 Competitive Analysis

3.2 Radiofrequency Ablation Systems

3.2.1 Industry Product Offering

3.2.2 Market Forecast

3.2.3 Competitive Analysis

3.3 Cryogenic Ablation Systems

3.3.1 Industry Product Offering

3.3.2 Market Forecast

3.3.3 Competitive Analysis

3.4 Focused Ultrasound Systems

3.4.1 Industry Product Offering

3.4.2 Market Forecast

3.4.3 Competitive Analysis

Section 4: Company Profiles

4.1 AFx, Inc.

4.2 ArgoMed

4.3 Arthrocare Corp.

4.4 AtriCure, Inc.

4.5 BARD EP

4.6 BEI Medical

4.7 BioSense Webster

4.8 Cardiac Pathways/EP Technologies/ Boston Scientific

4.9 Cardima

4.10 Celsion Corp.

4.11 Circon Corp.

4.12 Cryocath Technologies, Inc.

4.13 Cryomedical Sciences, Inc.

4.14 CryoGen

4.15 Curon Medical

4.16 EDAP Technomed

4.17 Endocare

4.18 Everest Medical/Gyrus

4.19 Focus Surgery

4.20 Galil Medical

4.21 Gynecare

4.22 Impres Medical

4.23 Insightec - TxSonics

4.24 Karl Storz Endoscopy-America

4.25 Medtronic

4.26 Microsulis

4.27 Novacept

4.28 Olympus America

4.29 OmniSonics

4.30 Prostalund

4.31 ProSurg/Injectx

4.32 Radio Therapeutics Corp.

4.33 Radionics

4.34 Richard Wolf Medical Instruments

4.35 RITA Medical

4.36 Somnus Medical Technologies

4.37 SURx

4.38 Thermatrx

4.39 Timm Medical Technologies

4.40 Urologix

4.41 Vida Med

Section 5: Glossary

Section 6: Company Listing

List of Exhibits

Exhibit ES-1: Overview of Therapies for BPH

Exhibit ES-2: TUMT Market Growth, by Competitor, 2000-2010 ($Millions)

Exhibit ES-3: Generation II Systems for Dysfunctional Uterine Bleeding, by Manufacturer

Exhibit ES-4: Anticipated Growth of Generation II Market, 2000-2010

Exhibit ES-5: Projections of Cancer Types to be Treated by Ablation Technologies, 2000–2010

Exhibit 1-1: Overview of Applications with Technologies

Exhibit 1-2: Comparison of Microwave, Radio Frequency and Ultrasound in the Body.

Exhibit 1-3: Overview of RF Companies, Products, and Applications

Exhibit 1-4: History of Cryoablation

Exhibit 1-5: Cryogenic Manufacturers and Applications

Exhibit 2-1: Generation I Manufacturers

Exhibit 2-2: Generation II Manufacturers

Exhibit 2-3: Cost Comparison of Generation II Products

Exhibit 2-4: Anticipated Growth of Generation II Market, 2000-2010

Exhibit 2-5: ESWL Procedures and Market Value

Exhibit 2-6: Overview of BPH Therapies

Exhibit 2-7: TUMT Market Share in Procedures, 2002

Exhibit 2-8: Projected TUMT Procedures by Manufacturer, 2000-2010

Exhibit 2-9: Projected TUMT Market, by Manufacturer, 2000-2010

Exhibit 2-10: TURP Procedures 2000-2010

Exhibit 2-11: Participants in the Atrial Fibrillation Market

Exhibit 2-12: Market Projections for Atrial fibrillation and Ventricular Tachycardia Markets, 2000-2010

Exhibit 2-13: Projected Procedures for TMR and PMR, 2000-2010

Exhibit 2-14: Photodynamic Technologies for Cancer Indications, 2000

Exhibit 3-1: Participants in TUMT Market

Exhibit 3-2: TUMT Procedures by Manufacturer, 2000-2010

Exhibit 3-3: Projected Market Shares for TUMT, 2000-2010

Exhibit 3-4: RF Ablation Applications by Clinical Specialty and Manufacturer

Exhibit 3-5: Projected Radiofrequency Procedures by Cancer Type, 2000-2010

Exhibit 3-6: Participants in Cryogenics Markets

Market Opportunities in Ablation Technology, 2002

April 2002

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Contact: Patrick Driscoll, (949) 859-3401.

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